Quick Take
- GPT-5 Pro re-ran an academic paper’s analyses programmatically and produced a detailed critique—identifying a previously unnoticed tabulation inconsistency—in 9 minutes 40 seconds.
- For inpatient pharmacy, wizard-style AI (examples: GPT-5 Pro, Claude 4.1 Opus, NotebookLM) can accelerate verification and modeling but requires verification literacy, curated output review, and strengthened governance to avoid silent errors and progressive deskilling.
Why it Matters
- Wizard-style AI generates rapid, expert-level outputs while hiding internal reasoning, creating a verification dilemma: clinicians must either perform impractical exhaustive checks or accept opaque recommendations, elevating medication-safety risk and complicating order-review workflows.
- Reliance on conjured outputs accelerates deskilling: pharmacists and trainees lose repeated practice and the judgment necessary to detect AI edge-case failures, reducing institutional resilience over time.
- Pharmacy must invest in governance, curated-output review, and ongoing audits—integrated with stewardship and clinical decision support (CDS)—otherwise these tools may create silent-error modes and strain limited resources.
What They Did
- Single-author, exploratory demonstrations: the author provided his book, ~140 blog posts, an Excel exercise, and his published paper to several commercial, closed, paywalled wizard AIs.
- He prompted NotebookLM to produce a video summary, Claude 4.1 Opus to ingest and transform a multi-tab Excel file and draft slides, and GPT-5 Pro to critique and re-run analyses on an academic paper.
- Validation was pragmatic and manual: the author reviewed outputs, spot-checked numbers and formulas, and confirmed one previously unnoticed tabulation inconsistency.
- Design note: these were informal, single-user demonstrations with no formal study design or systematic evaluation; models reported multi-step, agent-like behavior but remained opaque.
What They Found
- GPT-5 Pro re-ran the paper’s analyses in 9 minutes 40 seconds, produced a detailed critique, and identified a minor tabulation inconsistency—demonstrating how rapid re-analysis can surface data errors.
- Claude 4.1 Opus ingested a multi-tab Excel and, within minutes, transformed formulas and data into an updated spreadsheet and draft PowerPoint; outputs preserved instructional logic but contained a few formula or modelling choices needing human correction.
- NotebookLM synthesized the author’s book and ~140 blog posts into a video that reported cited metrics (e.g., MMLU, exam results), showing fast synthesis of large corpora but with opaque provenance.
- Practical implication: these wizard tools can accelerate verification, medication modeling, and guideline summarization, but their internal opacity makes pharmacist verification workflows and formal governance essential—it remains unclear which internal mechanisms actually produced the improvements.
Takeaways
- Use wizard-style AI (e.g., GPT-5 Pro, Claude) to recheck Excel-based dosing calculators, medication-use evaluations, and policy spreadsheets; have them surface inconsistencies and draft updates, but route outputs to an AI review queue/dashboard for pharmacist sign-off.
- Insert curated-output review wherever AI contributes to the chart or policy: require a pharmacist to annotate accepted/changed items and retain the prompt/output transcript in an auditable log.
- Run connoisseurship training (short, weekly drills) that maps when to summon the wizard, when to use co‑intelligence, and when to perform manual work; refresh guidance and lists quarterly.
- Operational principle: treat the wizard like a brilliant, secretive consultant—useful for rapid drafts and QC—but for high-risk medications and orders, pharmacists must lead, document the rationale, and limit AI to informing rather than deciding.
Strengths and Limitations
Strengths:
- Concrete, multi-task demonstrations (paper re-analysis, spreadsheet transformation, and video synthesis) illustrate rapid, practical, real-world wizard capabilities.
- Author performed hands-on verification and found a previously unnoticed tabulation inconsistency, evidencing the potential for AI to surface real data errors quickly.
Limitations:
- Informal, single-author, single-user demonstrations using closed, paywalled models limit reproducibility and generalizability.
- No systematic evaluation, quantitative metrics, or controlled comparisons were presented; the AI processes remained opaque, hindering auditability and rigorous validation.
Bottom Line
Wizard-style AI offers clear, practical value for pharmacy verification, modeling, and synthesis, but it must be validated locally, governed formally, and routed through pharmacist-led review and auditable workflows before routine clinical deployment.